Associations between central and brachial blood pressure in patients with hypertension and aortovascular disease: Implications for clinical practice: An Analysis and Review: Association between CBP and bBP

Abstract

The importance of central hemodynamic metrics such as Central blood pressure (CBP), which directly measure the pressure exerted by the cardiac muscle on the major arteries, offering a more direct assessment of cardiovascular workload compared to brachial blood pressure (bBP), which measures pressure against the walls of peripheral arteries. This review consolidates findings that evaluate the correlation between CBP and key markers of aortovascular disease. The growth of thoracic aortic aneurysm (TAA) is a significant component of aortovascular assessment. CBP correlates more precisely with arterial stiffness (AS), TAA growth, and cardiovascular diseases, providing a more reliable forecast of aortovascular diseases, adverse cardiovascular events (CVE), and organ damage than bBP. Integrating CBP into routine clinical practice could enhance aortovascular assessments and therapeutic strategies compared to bBP, especially by gaining a deeper understanding of aortic wave dynamics, which could fundamentally change aortovascular diagnostics and treatment. It is recommended to incorporate CBP into aortovascular and cardiovascular risk management. Further research is needed to confirm these aspects and to explore the practical implications of CBP in clinical settings.

Keywords: Brachial blood pressure; Cardiovascular events; Central blood pressure; Thoracic aortic aneurysm.