Activity determination of 177Lu using TDCR-Čerenkov method

Zihao Fan; Haoran Liu; Zhijie Yang; Juncheng Liang; Changhao Sun; Yifan Tian

doi:10.1016/j.apradiso.2025.111660

Activity determination of ¹⁷⁷Lu using TDCR-Čerenkov method

Appl Radiat Isot. 2025 Jan 6:217:111660. doi: 10.1016/j.apradiso.2025.111660. Online ahead of print.

Authors

Zihao Fan¹, Haoran Liu², Zhijie Yang¹, Juncheng Liang¹, Changhao Sun¹, Yifan Tian³

Affiliations

¹ National Institute of Metrology, Beijing, 100029, China.
² National Institute of Metrology, Beijing, 100029, China. Electronic address: liuhr@nim.ac.cn.
³ China University of Geosciences, Beijing, 100084, China.

PMID: 39793435
DOI: 10.1016/j.apradiso.2025.111660

Abstract

The accuracy of measuring the activity of ¹⁷⁷Lu is crucial for calibrating the instruments employed in clinical applications. To support the measurements of ¹⁷⁷Lu solution, the existing TDCR-Čerenkov method has been extended for this nuclide. The contribution of β and γ transitions from ¹⁷⁷Lu was taken into account in the extended method. Finally, the results obtained using this method, with an uncertainty of 0.62%, were found to be in good agreement with that derived from liquid scintillation counting.

Keywords: (177)Lu; Activity; TDCR; Čerenkov.