Selective excitation of bacteria enables growth suppression without antibiotics

Cell. 2025 Jan 9;188(1):1-3. doi: 10.1016/j.cell.2024.11.035.

Abstract

In a recently published article in Device, Saehyun Kim et al. report that selective excitation of bacteria can inhibit their proliferation in an antibiotic-free manner. We herein discuss the molecular and thermodynamic principles underlying this "selective excitability," which provides a new aspect to understand bacterial physiology.

MeSH terms

  • Anti-Bacterial Agents* / pharmacology
  • Bacteria* / drug effects
  • Bacteria* / growth & development
  • Bacteria* / metabolism
  • Bacterial Physiological Phenomena
  • Thermodynamics

Substances

  • Anti-Bacterial Agents