Complete genome sequences of two actinomycetes containing abyssomicin-like gene clusters: Kutzneria buriramensis DSM 45791 and Streptomyces sp. NL15-2K

Sam E Williams; David Faurdal; Tue S Jørgensen; Catherine R Back; Lynden D Rooms; Martin A Hayes; Christine L Willis; James E M Stach; Paul Curnow; Paul R Race

doi:10.1128/mra.01158-24

Complete genome sequences of two actinomycetes containing abyssomicin-like gene clusters: Kutzneria buriramensis DSM 45791 and Streptomyces sp. NL15-2K

Microbiol Resour Announc. 2025 Jan 15:e0115824. doi: 10.1128/mra.01158-24. Online ahead of print.

Authors

Affiliations

¹ Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
² School of Biochemistry, University of Bristol, Bristol, United Kingdom.
³ Discovery Sciences, Biopharmaceuticals R&D, AstraZeneca, Sweden, Mölndal.
⁴ School of Chemistry, University of Bristol, Bristol, United Kingdom.
⁵ School of Natural and Environmental Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.

PMID: 39812635
DOI: 10.1128/mra.01158-24

Abstract

Here, we report the resequencing, assembly, and annotation of two actinomycete genomes containing abyssomicin gene clusters. Kutzneria buriramensis DSM 45791 with a circular chromosome of 11,681,598 bp and 4 circular plasmids (14,175-207,548 bp) and Streptomyces sp. NL15-2K with a 12,368,159 bp linear genome and circular plasmid (11,584 bp).

Keywords: Kutzneria buriramensis; Oxford Nanopore Sequencing; Streptomyces NL15-2K; abyssomicin; actinomycetes; actinomycetes antibiotic discovery; biosynthetic gene clusters; genome mining for antibiotics; genomes; secondary metabolism.