Vaccination coverage, delay and loss to follow-up of the triple viral vaccine, in live births between 2017 and 2018 in Brazilian cities

Epidemiol Serv Saude. 2025 Jan 10;33(spe2):e20231218. doi: 10.1590/S2237-96222024v33e20231218.especial2.en. eCollection 2025.
[Article in English, Portuguese]

Abstract
in English, Spanish

Objective: To estimate measles-mumps-rubella vaccination coverage, delay and loss to follow-up in children up to 24 months old living in Brazilian cities.

Methods: Surveys and questionnaires with a retrospective cohort of live births in 2017-2018, analyzing vaccination coverage and sociodemographic data of children and families, based on vaccination card records and interviews.

Results: Valid coverage of first dose was 90.0% (95%CI 88.9;91.0) and 81.1% for the second dose (95%CI 79.8;82.4). Delay for both doses was 23.2% (95%CI 21.9;24.5) and loss to follow-up was 10.8% (95%CI 9.9;11.8). Socioeconomic stratum A had the lowest vaccination coverage and the higher the child's birth order, the lower the vaccination coverage for the second dose. Children whose mothers had 13 to 15 years of education had higher vaccination coverage.

Conclusion: Coverage did not meet the recommended target. Differentiated strategies to resolve difficulties in access, misinformation, and vaccination hesitancy will help improve vaccination coverage.

Objetivo: Estimar la cobertura de vacunación, retraso y la pérdida en el seguimiento de la vacuna triple vírica en niños de hasta 24 meses residentes en ciudades brasileñas.

Métodos: Encuestas y cuestionarios en una cohorte retrospectiva de nacidos vivos en 2017-2018, análisis de la cobertura y ​​datos sociodemográficos de niños y familias, a partir de registros de cartilla de vacunación y entrevistas.

Resultados: La cobertura válida para la primera dosis: 90,0% (IC95% 88,9;91,0); segunda: 81,1% (IC95% 79,8;82,4). El retraso de ambas: 23,2% (IC95% 21,9;24,5); pérdida en el seguimiento: 10,8% (IC95% 9,9;11,8). El estrato A tuvo la cobertura más baja y cuanto mayor el orden de nacimiento, menor la cobertura para la segunda dosis. Niños con madres que tienían entre 13 y 15 ãnos de escolatización presentaron una mayor cobertura.

Conclusión: La cobertura no alcanzó el recomendado, por lo que diferentes estrategias para resolver las dificultades de acceso, la desinformación y las dudas sobre las vacunas mejorarían la cobertura.

MeSH terms

  • Adolescent
  • Adult
  • Birth Order
  • Brazil
  • Child, Preschool
  • Cohort Studies
  • Educational Status
  • Female
  • Humans
  • Immunization Programs / statistics & numerical data
  • Infant
  • Infant, Newborn
  • Live Birth / epidemiology
  • Lost to Follow-Up
  • Male
  • Measles-Mumps-Rubella Vaccine* / administration & dosage
  • Retrospective Studies
  • Socioeconomic Factors
  • Surveys and Questionnaires
  • Time Factors
  • Vaccination Coverage* / statistics & numerical data
  • Vaccination* / statistics & numerical data

Substances

  • Measles-Mumps-Rubella Vaccine

Grants and funding

The survey that produced the data used in this study received funding from the Ministry of Health Department of Science and Technology and from the Conselho Nacional de Desenvolvimento Científico e Tecnológico, File No. 404131, with Professor José Cássio de Moraes as the principal investigator.