Cadaveric graft survival, clinical course, blood transfusion, HLA (A and B) match, and DR match in adult patients transplanted in one centre

Proc Eur Dial Transplant Assoc. 1979:16:359-65.

Abstract

The influence of blood transfusions, HLA, A and B, DR matching was studied in adult patients transplanted in one centre. The conclusions were: 1. Pre-transplant blood transfusion(s) are a prerequisite for graft acceptance. 2. In transfused patients with no HLA A and B mismatch, there is only 8% graft loss due to irreversible rejection. 3. In transfused patients with a functioning graft after six months, a decrease in the number of reversible rejection crises is observed in patients with no HLA A and B mismatch or with identity for HLA B7 or HLA B8. 4. Identity for HLA B7 or B8 also gives a higher chance of a late onset of the first rejection crisis.

MeSH terms

  • Antibody Specificity
  • Blood Transfusion*
  • Cadaver
  • Genetic Linkage
  • Graft Rejection
  • Graft Survival*
  • HLA Antigens*
  • Histocompatibility Testing
  • Humans
  • Kidney Transplantation*
  • Transplantation, Homologous

Substances

  • HLA Antigens