Symbiotic approach to drug design: antihypertensive beta-adrenergic blocking agents

J Med Chem. 1979 Nov;22(11):1284-90. doi: 10.1021/jm00197a002.
No abstract available

MeSH terms

  • Adrenergic beta-Antagonists / chemical synthesis*
  • Animals
  • Antihypertensive Agents / chemical synthesis*
  • Chemistry, Pharmaceutical
  • Dogs
  • Hypertension / physiopathology
  • Imidazoles / chemical synthesis
  • Imidazoles / pharmacology
  • Rabbits
  • Rats
  • Structure-Activity Relationship
  • Vasodilator Agents / chemical synthesis

Substances

  • Adrenergic beta-Antagonists
  • Antihypertensive Agents
  • Imidazoles
  • Vasodilator Agents