[Gonadotropic function in female Cushing's syndrome (author's transl)]

Ann Endocrinol (Paris). 1979 Jan-Feb;40(1):3-14.
[Article in French]

Abstract

Gonadotropic function has been studied without selection in 38 female patients with Cushing's syndrome followed during four years. The level of gonadotropins FSH and LH was low in all etiologies of the syndrome. LH-RH stimulation is normal in adrenal hyperplasia and adenoma, and very low in carcinoma. These abnormalities are cured after reduction of hypercorticism. The share of either cortisol or androgens is discussed. A predominant hypercortisolism blunting action on gonadotropic function is possible, cortisol being the common factor of Cushing's syndrome.

MeSH terms

  • Adenoma / complications
  • Adrenal Cortex Neoplasms / complications
  • Adult
  • Aged
  • Cushing Syndrome / blood
  • Cushing Syndrome / physiopathology*
  • Female
  • Follicle Stimulating Hormone / blood*
  • Follicle Stimulating Hormone / metabolism
  • Humans
  • Hydrocortisone / blood
  • Hyperplasia
  • Hypothalamo-Hypophyseal System / physiopathology
  • Luteinizing Hormone / blood*
  • Luteinizing Hormone / metabolism
  • Middle Aged
  • Pituitary Gland, Anterior / metabolism
  • Pituitary Gland, Anterior / physiopathology*

Substances

  • Luteinizing Hormone
  • Follicle Stimulating Hormone
  • Hydrocortisone