The incidence of cerebral amyloid angiopathy in Alzheimer's disease

Neurology. 1975 Feb;25(2):120-6. doi: 10.1212/wnl.25.2.120.

Abstract

The incidence and forms of cerebral amyloid angiopathy were studied in 15 cases of Alzheimer's disease using Congo red staining and polarization. Thirteen cases showed slight to severe involvement; two contained no amyloid vascular degeneration. There was a correlation between the presence of amyloid-rich plaques and cerebral amyloid angiopathy (especially the plaque-like angiopathy) but no correlation with "amyloid-poor" senile plaques or Alzheimer's neurofibrillary degeneration.

MeSH terms

  • Aged
  • Alzheimer Disease / complications
  • Alzheimer Disease / pathology*
  • Amyloidosis / etiology
  • Amyloidosis / pathology*
  • Autopsy
  • Brain / pathology
  • Cerebral Arterial Diseases / pathology*
  • Cerebral Arteries / pathology
  • Dementia / pathology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Staining and Labeling