Maternal smoking and cord blood immunity function

Clin Exp Immunol. 1979 May;36(2):256-9.

Abstract

Thymidine uptake in PHA-stimulated culture of cord blood cells from smoking mothers is greater than that from non-smoking mothers. There was no such difference when separated lymphocytes were studied; this suggests that smoking suppresses a suppressor cell. No difference was detected in haemoglobin, immunoglobulins, transferrin, cell counts, E-rosette counts and leucocyte mobility.

MeSH terms

  • Female
  • Fetal Blood / immunology*
  • Humans
  • Immunosuppression Therapy
  • Lymphocytes / immunology
  • Lymphocytes / metabolism
  • Phytohemagglutinins / pharmacology
  • Pregnancy
  • Pregnancy Complications*
  • Smoking*
  • Thymidine / metabolism

Substances

  • Phytohemagglutinins
  • Thymidine