Abstract
The occurrence of cellular hypersensitivity to rat liver mitochondria has been investigated in diabetic patients and control subjects by means of the leucocyte migration technique. Cellular hypersensitivity was demonstrated in 72% of insulin-dependent diabetics and 46% of non-insulin-dependent diabetics compared with 11% in the control group of normal individuals.
MeSH terms
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Adrenal Glands / immunology
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Animals
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Antigens*
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Cell Migration Inhibition
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Diabetes Mellitus / drug therapy
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Diabetes Mellitus / immunology*
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Humans
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Hypersensitivity, Delayed / immunology*
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Insulin / therapeutic use
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Kidney / immunology
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Leukocytes
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Mitochondria / immunology
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Mitochondria, Liver / immunology*
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Organ Specificity
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Rats / immunology
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Species Specificity