Creutzfeldt-Jakob disease (spongiform encephalopathy): transmission to the chimpanzee

Science. 1968 Jul 26;161(3839):388-9. doi: 10.1126/science.161.3839.388.

Abstract

Biopsy material taken from the brain of a patient with CreutzfeldtJakob disease with status spongiosus induced a similar fatal encephalopathy in a chimpanzee 13 months after inoculation.

MeSH terms

  • Animal Diseases*
  • Animals
  • Ataxia
  • Brain / pathology
  • Central Nervous System Diseases / pathology*
  • Dementia
  • Hominidae*
  • Humans
  • Kuru
  • Male
  • Middle Aged
  • Myoclonus