Rubella vaccine trial in children

Br Med J. 1969 May 31;2(5656):531-2. doi: 10.1136/bmj.2.5656.531.

Abstract

A study with RA 27/3 attenuated rubella virus vaccine (Plotkin strain) showed that this produced a significant antibody response in all of twenty-one vaccinated non-immune children without any appreciable marked clinical reactions. Serological examination of 53 non-immune and 29 immune siblings living in the same households failed to show any evidence of transmission of infection.

MeSH terms

  • Antibody Formation
  • Child
  • Child, Preschool
  • Female
  • Hemagglutination Inhibition Tests
  • Humans
  • Immunization
  • Infant
  • Joint Diseases / etiology
  • Rubella / prevention & control*
  • Rubella Vaccine
  • Rubella virus*
  • Viral Vaccines* / adverse effects

Substances

  • Rubella Vaccine
  • Viral Vaccines