Long-acting contraceptive agents: norethisterone esters of monoalkenyl and monoalkynyl acids

C G Francisco; R Freire; R Hernandez; J A Salazar; E Suarez; G A García de la Mora; J A Noguez; A Acosta; O Jimeno

doi:10.1016/0039-128x(83)90097-1

Long-acting contraceptive agents: norethisterone esters of monoalkenyl and monoalkynyl acids

Steroids. 1983 Mar;41(3):267-75. doi: 10.1016/0039-128x(83)90097-1.

Authors

C G Francisco, R Freire, R Hernandez, J A Salazar, E Suarez, G A García de la Mora, J A Noguez, A Acosta, O Jimeno

PMID: 6658874
DOI: 10.1016/0039-128x(83)90097-1

Abstract

The synthesis of nine new esters of norethisterone (17 alpha-ethynyl-17 beta-hydroxyestr-4-en-3-one) is described, with the esterifying acids bearing an acetylenic or olefinic function in a chain of eight or nine carbon atoms, for evaluation as long-acting contraceptive agents.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Delayed-Action Preparations
Esters
Indicators and Reagents
Magnetic Resonance Spectroscopy
Mass Spectrometry
Norethindrone / analogs & derivatives*
Norethindrone / chemical synthesis
Structure-Activity Relationship

Substances

Delayed-Action Preparations
Esters
Indicators and Reagents
Norethindrone