Pulmonary infiltrates associated with naproxen

JAMA. 1984 Jan 6;251(1):65-6.

Abstract

Pulmonary infiltrates developed in three middle-aged women while receiving naproxen sodium. Weakness, fatigue, cough, low-grade fever, and eosinophilia in blood and/or sputum were common to all. All symptoms and findings resolved within a few days after discontinuing naproxen therapy in two cases and with use of corticosteroids (prednisone) in one case. A hypersensitivity reaction due to naproxen seemed to be the likely cause.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Arthritis, Rheumatoid / drug therapy
  • Drug Hypersensitivity / etiology
  • Female
  • Humans
  • Middle Aged
  • Naproxen / adverse effects*
  • Pulmonary Eosinophilia / chemically induced*
  • Pulmonary Eosinophilia / diagnostic imaging
  • Radiography

Substances

  • Naproxen