Gonad-specific uptake of H-Y antigen in the chicken

J Reprod Immunol. 1984 Jan;6(1):11-7. doi: 10.1016/0165-0378(84)90037-8.

Abstract

Soluble H-Y antigen of the mouse is bound in testicular cells of the ZZ chicken, and not in cells of the ZZ blood, bursa, kidney, liver or spleen. This implies occurrence in birds of a gonad-specific receptor for H-Y. Since H-Y is present in ZW females and not in ZZ males, reaction of H-Y and its gonadal receptor may be critical to development of the ZW ovary.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Chickens / immunology*
  • Cytotoxicity, Immunologic
  • Female
  • H-Y Antigen / metabolism*
  • Male
  • Mice
  • Mice, Inbred BALB C
  • Mice, Inbred C57BL
  • Organ Specificity
  • Ovary / immunology*
  • Ovary / metabolism
  • Receptors, Antigen / physiology
  • Testis / immunology*
  • Testis / metabolism

Substances

  • H-Y Antigen
  • H-Y antigen receptor
  • Receptors, Antigen