Cross antigenic and allergenic properties of the house dust mite Dermatophagoides farinae and the storage mite Tyrophagus putrescentiae

J Allergy Clin Immunol. 1984 Aug;74(2):172-9. doi: 10.1016/0091-6749(84)90282-3.

Abstract

The crossed antigenicity and allergenicity of the storage mite Tyrophagus putrescentiae (TP) and the house dust mite Dermatophagoides farinae (DF) were characterized by means of crossed immunoelectrophoresis and crossed radioimmunoelectrophoresis. DF extracts exhibited 32 antigens and as many as eight were demonstrated to be allergens. DF feces exhibited 20 antigens and six of these were allergens. Twenty antigens and two allergens were demonstrated for TP. Two antigenic and allergenic determinants were shared by DF and TP, and two determinants were also shared by DF feces and TP feces. TP feces and DF shared two antigenic and allergenic determinants. Our results demonstrated that the two mites and their feces extracts contain multiple antigens and allergens.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Allergens / immunology
  • Antigens / immunology*
  • Cross Reactions
  • Dust
  • Feces / immunology
  • Flour
  • Humans
  • Immunoelectrophoresis, Two-Dimensional / methods
  • Mites / immunology*
  • Radioimmunoassay
  • Skin Tests
  • Triticum

Substances

  • Allergens
  • Antigens
  • Dust