The formation of arylating and alkylating metabolites of phenacetin in hamsters and hamster liver microsomes

Mol Pharmacol. 1981 Jan;19(1):140-5.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acetylcysteine / metabolism
  • Alkylation
  • Animals
  • Ascorbic Acid / pharmacology
  • Biotransformation
  • Carbon Dioxide / metabolism
  • Cricetinae
  • Cysteine / metabolism
  • Glutathione / metabolism
  • In Vitro Techniques
  • Microsomes, Liver / metabolism*
  • Phenacetin / metabolism*
  • Protein Binding / drug effects

Substances

  • Carbon Dioxide
  • Phenacetin
  • Glutathione
  • Cysteine
  • Ascorbic Acid
  • Acetylcysteine