Crescentic glomerulonephritis complicating idiopathic membranous glomerulonephropathy

South Med J. 1983 May;76(5):664-7. doi: 10.1097/00007611-198305000-00036.

Abstract

We describe the course of a patient with multiple rectal abscesses and progressive renal dysfunction. A renal biopsy demonstrated a membranous glomerulopathy associated with extensive crescent formation. No underlying cause for the glomerulonephritis could be identified and, specifically, the anti-GBM antibody present in other similar cases was not found. There appears to be a subset of patients with membranous glomerulopathy in whom crescents develop with rapid loss of renal function. Anti-GBM antibody is not necessary in the pathogenesis of this lesion.

Publication types

  • Case Reports

MeSH terms

  • Abscess / complications
  • Adult
  • Basement Membrane / pathology
  • Basement Membrane / ultrastructure
  • Biopsy
  • Glomerulonephritis / diagnosis
  • Glomerulonephritis / etiology
  • Glomerulonephritis / pathology*
  • Humans
  • Kidney Failure, Chronic / etiology
  • Kidney Failure, Chronic / therapy
  • Kidney Glomerulus / pathology*
  • Male
  • Microscopy, Electron
  • Rectal Diseases / complications
  • Renal Dialysis