[Microestimation of haemoglobins A2 and F by measurement of their peroxydase activity (author's transl)]

Ann Biol Clin (Paris). 1978;36(2):75-7.
[Article in French]

Abstract

A microtechnique of evaluation for the haemoglobins A2 and F is presented, in which the final measurement is made more sensitive by evaluation of peroxidatic activity. Haemoglobin A2 is previously separated by chromatography on a very small column of DEAE cellulose and haemoglobin F is obtained through a microtechnique of alkaline precipitation. The sensitivity of this evaluation is increased by a factor of 20.25 microliter of hemolyzate are enough for a determination. Results obtained are in accordance with those given by the classical methods.

Publication types

  • English Abstract

MeSH terms

  • Fetal Hemoglobin / analysis*
  • Hemoglobin A / analysis*
  • Hemoglobinometry / methods
  • Humans
  • Microchemistry / methods
  • Peroxidases / blood*
  • Reference Values

Substances

  • Hemoglobin A
  • Fetal Hemoglobin
  • Peroxidases