Heterozygous C2-deficiency and myasthenia gravis

Neurology. 1980 Aug;30(8):871-3. doi: 10.1212/wnl.30.8.871.

Abstract

Complement deficiency states in myasthenia gravis (MG) have not been reported previously. We describe a 19-year-old woman with typical MG and heterozygous C2 deficiency, along with HLA typing of the patient and her immediate family.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acetylcholine / immunology
  • Adult
  • Antibodies / analysis
  • Complement C2 / deficiency*
  • Complement C2 / genetics
  • Complement C3 / analysis
  • Complement C4 / analysis
  • Female
  • Genotype
  • HLA Antigens / analysis
  • HLA Antigens / genetics
  • Heterozygote
  • Humans
  • Myasthenia Gravis / immunology*
  • Pedigree
  • Receptors, Cholinergic / immunology

Substances

  • Antibodies
  • Complement C2
  • Complement C3
  • Complement C4
  • HLA Antigens
  • Receptors, Cholinergic
  • Acetylcholine