Abstract
In patients with SLE dsDNA binding activity, C3 and C4 levels are correlated with the clinical course of the nephritis. In fact the study of these serological parameters has a prognostic value in patients treated with methylprednisolone pulse therapy. This treatment can rapidly normalize an acute phase.
MeSH terms
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Adolescent
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Adult
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Antibodies / analysis*
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Complement C3 / analysis
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Complement C4 / analysis
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Complement System Proteins / analysis*
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DNA / immunology*
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Female
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Humans
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Lupus Erythematosus, Systemic / drug therapy
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Lupus Erythematosus, Systemic / immunology*
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Male
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Methylprednisolone / administration & dosage
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Methylprednisolone / therapeutic use*
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Middle Aged
Substances
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Antibodies
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Complement C3
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Complement C4
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Complement System Proteins
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DNA
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Methylprednisolone