Massive locally extensive prostate cancer

Urology. 1994 Feb;43(2):242-3. doi: 10.1016/0090-4295(94)90054-x.

Abstract

A massive, locally extensive adenocarcinoma of the prostate (2,246 ccm) presenting as constipation and a palpable abdominal mass, was treated with androgen deprivation resulting in a 94 percent reduction in tumor size, and relief of symptoms. Serum prostate-specific antigen was reduced from 4,029 to 0.4 ng/mL, after hormonal therapy was combined with radiation treatments for local disease control.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / complications
  • Adenocarcinoma / pathology*
  • Adenocarcinoma / therapy
  • Aged
  • Combined Modality Therapy
  • Constipation / etiology
  • Flutamide / therapeutic use
  • Humans
  • Leuprolide / therapeutic use
  • Male
  • Prostate / pathology*
  • Prostate-Specific Antigen / blood
  • Prostatic Neoplasms / complications
  • Prostatic Neoplasms / pathology*
  • Prostatic Neoplasms / therapy
  • Radiotherapy Dosage

Substances

  • Flutamide
  • Prostate-Specific Antigen
  • Leuprolide