Abstract
We studied the prognoses of unresectable liver tumors, including 31 colorectal cancers and 10 gastric cancers treated by intra-arterial infusion chemotherapy using an implantable reservoir. Adriamycin, epirubicin, or cisplatin were administered intermittently early on. Cisplatin and 5-FU combined therapy were given later. In nine with colorectal metastases and six with gastric metastases, metastatic lesions decreased, and in 4 patients with metastatic lesions could be resected. But in many patients, hepatic and other organ recurrences were observed. We need to try many other treatments.
Publication types
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Clinical Trial
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English Abstract
MeSH terms
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Adenocarcinoma / drug therapy*
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Adenocarcinoma / secondary
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Aged
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Cisplatin / administration & dosage
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Colonic Neoplasms / pathology
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Doxorubicin / administration & dosage
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Epirubicin / administration & dosage
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Female
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Fluorouracil / administration & dosage
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Humans
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Infusion Pumps, Implantable*
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Infusions, Intra-Arterial
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Liver Neoplasms / drug therapy*
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Liver Neoplasms / secondary
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Male
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Middle Aged
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Stomach Neoplasms / pathology
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Treatment Outcome
Substances
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Epirubicin
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Doxorubicin
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Cisplatin
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Fluorouracil