Differential diagnosis in spinal and bulbar muscular atrophy clinical and molecular aspects

J Neurol Sci. 1995 May:129 Suppl:56-7. doi: 10.1016/0022-510x(95)00064-9.

Abstract

Kennedy disease is caused by an enlarged trinucleotide repeat sequence within the androgen receptor gene. We report here seven male patients with a benign motor neuron syndrome highly analogous to Kennedy disease but with a normal trinucleotide repeat.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Base Sequence
  • Creatine Kinase / blood
  • DNA / analysis
  • Diagnosis, Differential
  • Electrophysiology
  • Humans
  • Male
  • Middle Aged
  • Molecular Sequence Data
  • Motor Neuron Disease / diagnosis*
  • Motor Neuron Disease / genetics
  • Muscular Atrophy, Spinal / diagnosis*
  • Muscular Atrophy, Spinal / genetics
  • Receptors, Androgen / genetics

Substances

  • Receptors, Androgen
  • DNA
  • Creatine Kinase