Management of ductal carcinoma in situ of the breast

Ann R Coll Surg Engl. 1995 May;77(3):163-7.

Abstract

The advent of mammographic breast screening has increased the detection of ductal carcinoma in situ (DCIS), which now accounts for 15-20% of all breast cancer. While symptomatic DCIS has been treated satisfactorily by mastectomy, this may be an overtreatment of smaller screen-detected lesions. Although local excision, with or without radiotherapy, is associated with a significant risk of local recurrence of DCIS or invasive cancer, salvage surgery is usually successful. The long-term breast-specific mortality rate of treatment by mastectomy and local excision are similar. Whereas mastectomy is still appropriate for women with lesions > 30 mm in diameter or centrally placed and for those women who demand the best possible disease-free survival, local surgery should otherwise be considered.

Publication types

  • Review

MeSH terms

  • Breast Neoplasms / radiotherapy
  • Breast Neoplasms / surgery*
  • Carcinoma in Situ / radiotherapy
  • Carcinoma in Situ / surgery*
  • Carcinoma, Ductal, Breast / radiotherapy
  • Carcinoma, Ductal, Breast / surgery*
  • Female
  • Humans
  • Mass Screening
  • Mastectomy / methods*
  • Neoplasm Recurrence, Local
  • Radiotherapy, Adjuvant