Abstract
Six multigenerational pedigrees containing multiple cases of manic-depression were genotyped with a DNA polymorphism for the norepinephrine transporter (NET) gene. Using both parametric and nonparametric methods, no evidence of linkage between manic-depression and the NET gene was found.
Publication types
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Adolescent
-
Adult
-
Bipolar Disorder / genetics*
-
Carrier Proteins / genetics*
-
Female
-
Humans
-
Lod Score*
-
Male
-
Norepinephrine Plasma Membrane Transport Proteins
-
Pedigree
-
Polymorphism, Restriction Fragment Length
-
Symporters*
Substances
-
Carrier Proteins
-
Norepinephrine Plasma Membrane Transport Proteins
-
SLC6A2 protein, human
-
Symporters