The aim of this study was the instrumental evaluation of ultrasound therapy in patients with periarthritis of the shoulder, with regard to studies that show doubts about the real effectiveness of the antiinflammatory action of ultrasound. Two groups of subjects were studied, periarthritis versus normal patients. Clinical evaluation and instrumental measures (telethermography) were performed before and after ultrasound therapy. These data were statistically analyzed and constant variations were found, according to clinical evaluation of the patients. Therefore results of this study demonstrated a real influence of ultrasound therapy on periarthritis of the shoulder.