Apoptosis research enters the ICE age

Structure. 1995 Feb 15;3(2):143-5. doi: 10.1016/s0969-2126(01)00144-7.

Abstract

Recent elucidation of the structure of interleukin-1 beta-converting enzyme (ICE), a protease with sequence homology to a nematode protein associated with programmed cell death, opens a new chapter in the study of how proteases may control cellular suicide.

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Apoptosis / physiology*
  • Caenorhabditis elegans Proteins
  • Caspase 1
  • Caspases*
  • Cysteine Endopeptidases* / chemistry
  • Cysteine Endopeptidases* / genetics
  • Cysteine Endopeptidases* / physiology
  • Helminth Proteins / genetics
  • Helminth Proteins / physiology
  • Metalloendopeptidases / genetics
  • Metalloendopeptidases / physiology
  • Molecular Sequence Data
  • Sequence Homology, Amino Acid

Substances

  • Caenorhabditis elegans Proteins
  • Helminth Proteins
  • Caspases
  • Cysteine Endopeptidases
  • ced-3 protein, C elegans
  • Caspase 1
  • Metalloendopeptidases
  • protease resembling ICE