[A heart transplant in a patient with doxorubicin-induced myocardiopathy as a complication of the treatment of a lymphoma]

Rev Esp Cardiol. 1994 Nov;47(11):777-9.
[Article in Spanish]

Abstract

We present the case of a young man who developed severe cardiomyopathy eight years after receiving high-dose doxorubicin therapy as treatment for diffuse lymphoblastic lymphoma. He underwent cardiac transplantation and eighteen months later the tumor has not recurred and the patient has no cardiac symptoms.

Publication types

  • Case Reports
  • English Abstract
  • Review

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Cardiomyopathy, Dilated / chemically induced*
  • Cardiomyopathy, Dilated / pathology
  • Cardiomyopathy, Dilated / surgery*
  • Cyclophosphamide / administration & dosage
  • Daunorubicin / administration & dosage
  • Doxorubicin / administration & dosage
  • Doxorubicin / adverse effects*
  • Heart Transplantation*
  • Humans
  • Male
  • Methotrexate / administration & dosage
  • Myocardium / pathology
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • Prednisone / administration & dosage
  • Time Factors
  • Vincristine / administration & dosage

Substances

  • Vincristine
  • Doxorubicin
  • Cyclophosphamide
  • Prednisone
  • Methotrexate
  • Daunorubicin

Supplementary concepts

  • CHOP protocol
  • LSA2-L2 protocol