Inhibition of interleukin-1-stimulated collagen degradation in cartilage explants

Ann N Y Acad Sci. 1994 Sep 6:732:395-7. doi: 10.1111/j.1749-6632.1994.tb24764.x.
No abstract available

MeSH terms

  • Amides / pharmacology*
  • Animals
  • Cattle
  • Collagen / metabolism*
  • Collagenases / metabolism*
  • Culture Techniques
  • Humans
  • Interleukin-1 / pharmacology*
  • Kinetics
  • Metalloendopeptidases / antagonists & inhibitors*
  • Nasal Septum / drug effects
  • Nasal Septum / enzymology*
  • Recombinant Proteins / pharmacology
  • Time Factors
  • Tyrosine / analogs & derivatives*
  • Tyrosine / pharmacology

Substances

  • Amides
  • Interleukin-1
  • Recombinant Proteins
  • N-(2-isobutyl-3-(N'-hydroxycarbonylamido)propanoyl)-O-methyltyrosinemethylamide
  • Tyrosine
  • Collagen
  • Collagenases
  • Metalloendopeptidases