An evaluation of the microbial retention performance of three ventilator-circuit filters

Intensive Care Med. 1994;20(3):233-7. doi: 10.1007/BF01704708.

Abstract

Objectives: to determine and compare the microbial retention efficiency of 3 types of heat and moisture exchange (HME) filters.

Design: randomised prospective study.

Setting: Intensive Care Unit at the Middlesex Hospital and the microbiology laboratory of the Department of Academic Microbiology, University College London Medical School.

Measurements and results: An aerosol challenge to each filter using a suspension containing. S. marcescens and the bacteriophage MS2. In total 45 filters of 3 types were tested, 15 previously unused and 30 that had been used in ventilator circuits of 30 patients. The 3 types of filter generally had microbial retention efficiencies of > 99.99% for both S. marcescens and the bacteriophage MS2.

Conclusion: The 3 types of HME filter were effective microbial filters and comparable in their microbial retention.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Aerosols
  • Equipment Contamination*
  • Equipment Design
  • Evaluation Studies as Topic
  • Filtration / instrumentation*
  • Humans
  • Humidity
  • Intensive Care Units
  • Levivirus*
  • Particle Size
  • Prospective Studies
  • Respiration, Artificial*
  • Serratia marcescens*

Substances

  • Aerosols