Abstract
Astroviruses have been adapted to culture by serial blind passage in primary human embryo cells. All viruses thus adapted possess a 45-nucleotide deletion relative to fecal viruses or isolates made in CaCo-2 cells; this deletion may be responsible for the change in host cell range.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Base Sequence
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Cells, Cultured
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DNA Primers / chemistry
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Humans
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In Vitro Techniques
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Mamastrovirus / genetics*
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Molecular Sequence Data
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Sequence Alignment
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Sequence Deletion
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Sequence Homology, Amino Acid
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Viral Proteins / chemistry
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Viral Proteins / genetics
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Virus Replication
Substances
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DNA Primers
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Viral Proteins