Influence of intact and partially hydrolysed guar gum on iron utilization in rats fed on iron-deficient diets

Comp Biochem Physiol Physiol. 1994 Sep;109(1):75-82. doi: 10.1016/0300-9629(94)90313-1.

Abstract

Effects of partially hydrolysed guar gum (PHGG) or intact guar gum (GG) on iron utilization in rats fed on several iron-deficient diets were examined. Hemoglobin, serum iron and iron storage in liver of rats fed on iron-deficient diets as a control group (without PHGG and GG) significantly decreased, while those of the test group fed together with PHGG or GG were unchanged. In an iron balance test for 3 days, administration of PHGG or GG caused an increase in iron absorption. The results suggested that PHGG or its metabolites increase the bioavailability of dietary iron in deficiency.

MeSH terms

  • Absorption / drug effects
  • Animals
  • Biological Availability
  • Diet*
  • Dietary Fiber
  • Galactans / chemistry
  • Galactans / pharmacology*
  • Hydrolysis
  • Iron / administration & dosage
  • Iron / metabolism*
  • Iron / pharmacokinetics
  • Mannans / chemistry
  • Mannans / pharmacology*
  • Plant Gums
  • Rats
  • Rats, Wistar
  • Viscosity

Substances

  • Dietary Fiber
  • Galactans
  • Mannans
  • Plant Gums
  • Iron
  • guar gum