A 43-year-old male simultaneously presented a bronchial granular cell myoblastoma affecting the bronchi of the lower right lobe, and a bronchogenic epidermoid carcinoma with mediastinal spread. In both cases diagnosis was established through bronchial and mediastinal biopsies, with posterior immunohistochemical evaluation to confirm the nature of the neoplastic lesions. The clinicopathological characteristics of this rare observation not previously reported in our country are commented.