New antibiotics, griseusins A and B. Isolation and characterization

N Tsuji; M Kobayashi; Y Wakisaka; Y Kawamura; M Mayama

doi:10.7164/antibiotics.29.7

New antibiotics, griseusins A and B. Isolation and characterization

J Antibiot (Tokyo). 1976 Jan;29(1):7-9. doi: 10.7164/antibiotics.29.7.

Authors

N Tsuji, M Kobayashi, Y Wakisaka, Y Kawamura, M Mayama

PMID: 819406
DOI: 10.7164/antibiotics.29.7

Abstract

New antibiotics, griseusins A and B were isolated from a strain of Streptomyces griseus. Both antibiotics have a 5-hydroxy-1, 4-naphthoquinone chromophore and their molecular formulae were determined to be C22H20O10 and C22H22O10, respectively. The griseusins are active against gram-positive bacteria.

MeSH terms

Animals
Anti-Bacterial Agents* / biosynthesis
Anti-Bacterial Agents* / isolation & purification
Anti-Bacterial Agents* / pharmacology
Bacteria / drug effects
Bacterial Infections / drug therapy
Fermentation
Mice
Solubility
Streptomyces griseus / metabolism

Substances

Anti-Bacterial Agents