Abstract
Of 20 blood specimens testing positive for cytomegalovirus antigen after immediate processing, 19 (95%) remained positive when kept at room temperature for 24 h before processing. Quantitative antigenemia decreased by an average of 44% after storage. Compared with acetone fixation, formaldehyde fixation showed improved readability, fewer artifacts, and a higher degree of sensitivity.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Acetone
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Antigens, Viral / blood*
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Cytomegalovirus / immunology*
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Cytomegalovirus / isolation & purification*
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Cytomegalovirus Infections / diagnosis*
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Cytomegalovirus Infections / microbiology
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Evaluation Studies as Topic
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Fixatives
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Formaldehyde
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Humans
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Sensitivity and Specificity
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Viremia / diagnosis*
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Viremia / microbiology
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Virology / methods
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Virology / statistics & numerical data
Substances
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Antigens, Viral
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Fixatives
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Acetone
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Formaldehyde