A new myosin I gene in Drosophila

Biochem Biophys Res Commun. 1993 Sep 30;195(3):1280-8. doi: 10.1006/bbrc.1993.2182.

Abstract

We have identified and cloned a new myosin-I cDNA, myosin 61F, from Drosophila melanogaster. The sequence of myosin 61F cDNA shows high similarity to vertebrate myosin-I sequences. Myosin 61F is most similar to bovine myosin Ib, showing 78% similarity and 63% identity. Myosin 61F is a single copy gene which maps to polytene region 61F, a genomic region with several potential myosin mutations. The identification of a myosin-I gene in Drosophila will allow genetic analysis of myosin-I function in a metazoan organism.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Drosophila / genetics*
  • Genes, Insect / genetics*
  • Molecular Sequence Data
  • Multigene Family / genetics*
  • Myosins / genetics*
  • Myosins / immunology
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Sequence Homology, Amino Acid

Substances

  • Myosins

Associated data

  • GENBANK/D37827
  • GENBANK/L13070
  • GENBANK/L16877
  • GENBANK/L16878
  • GENBANK/L19108
  • GENBANK/L19109
  • GENBANK/L19111
  • GENBANK/L19112
  • GENBANK/L19956
  • GENBANK/L19957