Elevated estrogen 16 alpha-hydroxylase activity: is this a genotoxic or nongenotoxic biomarker in human breast cancer risk?

J Natl Cancer Inst. 1993 Dec 1;85(23):1888-91. doi: 10.1093/jnci/85.23.1888.
No abstract available

Publication types

  • Comment
  • Editorial
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aryl Hydrocarbon Hydroxylases*
  • Biomarkers, Tumor / metabolism
  • Breast Neoplasms / enzymology*
  • Cytochrome P-450 Enzyme System / metabolism*
  • Estradiol / metabolism
  • Female
  • Humans
  • Oxidation-Reduction
  • Polymorphism, Genetic / physiology
  • Receptors, Estrogen / metabolism
  • Risk Factors
  • Steroid 16-alpha-Hydroxylase
  • Steroid Hydroxylases / metabolism*

Substances

  • Biomarkers, Tumor
  • Receptors, Estrogen
  • Estradiol
  • Cytochrome P-450 Enzyme System
  • Steroid Hydroxylases
  • Aryl Hydrocarbon Hydroxylases
  • Steroid 16-alpha-Hydroxylase