Production and isolation of cerexins C and D studies on antibiotics from the genus Bacillus. XVII

J Antibiot (Tokyo). 1976 Dec;29(12):1281-5. doi: 10.7164/antibiotics.29.1281.

Abstract

From the culture broth of Bacillus cereus 60-6, in which antibiotic production was improved a new antibiotic, named cerexin C, was isolated. Similarly, a new antibiotic, cerexin D was isolated from the culture broth of Bacillus cereus Gp-3. Cerexins C and D are closely related to cerexins A and B in their physico-chemical and antimicrobial properties. In fact cerexins C and D are peptides essentially identical with cerexins A and B except for the presence of a lysine residue in place of the gamma-hydroxylysine residue.

MeSH terms

  • Amino Acids / analysis
  • Anti-Bacterial Agents / biosynthesis
  • Anti-Bacterial Agents / isolation & purification*
  • Anti-Bacterial Agents / pharmacology
  • Bacillus cereus / metabolism*
  • Bacteria / drug effects
  • Chemical Phenomena
  • Chemistry
  • Fatty Acids / analysis
  • Hydrolysis
  • Peptide Biosynthesis
  • Peptides / isolation & purification*
  • Peptides / pharmacology

Substances

  • Amino Acids
  • Anti-Bacterial Agents
  • Fatty Acids
  • Peptides