Fistulae following laryngectomy in patients treated with irradiation

J Laryngol Otol. 1993 Dec;107(12):1136-9. doi: 10.1017/s0022215100125484.

Abstract

The development of fistulae following 197 consecutive laryngectomies performed from 1980 to 1987 have been examined. Fistulae were present in 28 patients (14 per cent). Age, T-classification, daily level of radiation dose and the time lapse between diagnosis and operation did not seem to influence the rate of fistula development. The study indicates that there is a two to three per cent risk of fistula development when a primary laryngectomy is performed. Fistula formation increased to about 10 to 12 per cent following radiotherapy, with an additional increase whenever previous operations on the neck had been done and/or if the disease demanded more extensive surgery. The study also indicates that the risk for fistula development is less when an experienced surgeon performs the operation.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Combined Modality Therapy / adverse effects
  • Cutaneous Fistula / etiology*
  • Female
  • Fistula / etiology*
  • Humans
  • Hypopharyngeal Neoplasms / radiotherapy
  • Hypopharyngeal Neoplasms / surgery
  • Laryngeal Neoplasms / radiotherapy
  • Laryngeal Neoplasms / surgery
  • Laryngectomy / adverse effects*
  • Male
  • Middle Aged
  • Pharyngeal Diseases / etiology*
  • Radiotherapy / adverse effects
  • Radiotherapy Dosage
  • Risk Factors