The allergenic airborne pollen of Cupressaceae was surveyed in the area of Bari (Southern Italy) over an 8-year period (1982-1989). A Burkard 7-day recording volumetric spore trap was used for the aerobiologic investigation. The results showed a notable annual pollinic presence of airborne Cupressaceae pollen, the largest amount recorded in winter and early spring. Remarkable fluctuations of the Cupressaceae pollen counts in a 2-year cycle were also observed. The features of the main pollen season are described. In particular, its duration was found to be on average 45 days. A study of Cupressaceae trees distribution indicated that the most widespread genus was Cupressus, represented in particular by the species Cupressus arizonica Green and Cupressus Sempervirens L. The employment of these trees for reforestation and garden-use has increased considerably in the last 40 years. These findings can also be of interest in other countries where Cupressaceae allergy has been reported, particularly in the Mediterranean basin and in North America.