Ascaridole as a pharmacologically active principle of "Paico," a medicinal Peruvian plant

Chem Pharm Bull (Tokyo). 1993 Jul;41(7):1309-11. doi: 10.1248/cpb.41.1309.

Abstract

"Paico," Chenopodium ambrosioides L., is a traditional Peruvian medicine which is considered to be nervine, antirheumatic, anthelmintic, etc. An attempt was made to isolate the component having sedative and/or analgesic properties from "Paico" and "Aritasou" (the Japanese name for C. ambrosioides). Ascaridole was identified as the active principle in both materials.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analgesics / isolation & purification*
  • Analgesics / pharmacology
  • Animals
  • Anthelmintics / isolation & purification*
  • Anthelmintics / pharmacology
  • Cyclohexane Monoterpenes
  • Hypnotics and Sedatives / isolation & purification*
  • Hypnotics and Sedatives / pharmacology
  • Male
  • Mice
  • Mice, Inbred Strains
  • Monoterpenes*
  • Peroxides*
  • Peru
  • Plants, Medicinal / chemistry*
  • Terpenes / isolation & purification*
  • Terpenes / pharmacology

Substances

  • Analgesics
  • Anthelmintics
  • Cyclohexane Monoterpenes
  • Hypnotics and Sedatives
  • Monoterpenes
  • Peroxides
  • Terpenes
  • ascaridole