Measurement of whole temporal lobe and hippocampus for MR volumetry: normative data

Neurology. 1993 Oct;43(10):2006-10. doi: 10.1212/wnl.43.10.2006.

Abstract

We measured the volumes of the entire length of temporal lobe and hippocampal formation from coronal images in 29 healthy young adults to take into account normal side-to-side variation. Although whole-brain, temporal lobe, and left hippocampal volumes were significantly smaller in women, normalizing measurements for the whole brain eliminated intersex temporal lobe and hippocampal differences. There was a weak but significant inverse correlation between age and normalized hippocampal, but not temporal lobe or whole-brain, volume. In contrast to previous studies, we found no significant side-to-side differences in the sizes of temporal lobes or hippocampi. When performing MR volumetry, it is important to include the entire length of the hippocampal formation.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Brain / anatomy & histology*
  • Female
  • Hippocampus / anatomy & histology*
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Male
  • Reference Values
  • Sex Factors
  • Temporal Lobe / anatomy & histology*