Abstract
In a randomized, controlled trial, the lungs of infants with respiratory distress syndrome were ventilated with either a helium-oxygen mixture or a nitrogen-oxygen mixture. In the helium-oxygen group, infants required a lower inspired oxygen concentration and a shorter duration of ventilation. There were also fewer deaths and fewer cases of bronchopulmonary dysplasia in the helium-oxygen group.
Publication types
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Clinical Trial
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Randomized Controlled Trial
MeSH terms
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Airway Resistance
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Blood Pressure
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Bronchopulmonary Dysplasia / etiology
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Double-Blind Method
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Helium / therapeutic use*
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Humans
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Infant, Newborn
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Intubation, Intratracheal
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Nitrogen / therapeutic use*
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Oxygen / blood
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Oxygen / therapeutic use*
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Pulmonary Atelectasis / etiology
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Respiration / physiology
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Respiration, Artificial*
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Respiratory Distress Syndrome, Newborn / therapy*
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Survival Rate
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Treatment Outcome
Substances
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Helium
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heliox
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Nitrogen
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Oxygen