A neurophysiological study on the P300 component of event-related potentials in Hakim-Adams syndrome

Eur Neurol. 1993;33(1):44-7. doi: 10.1159/000116899.

Abstract

We have explored the variability of P300 event-related potentials in patients affected by Hakim-Adams syndrome, with raised or intermittent intracranial pressure, treated with surgical cerebrospinal fluid shunting. The clinical utility of P300 is confirmed in the light of the improvement of neurophysiological data after the surgical procedure, parallel with amelioration of neuropsychological performances.

MeSH terms

  • Aged
  • Arousal / physiology*
  • Attention / physiology*
  • Cerebrospinal Fluid Pressure / physiology*
  • Cerebrospinal Fluid Shunts
  • Dementia / physiopathology*
  • Dementia / surgery
  • Evoked Potentials, Auditory / physiology*
  • Female
  • Humans
  • Hydrocephalus / physiopathology*
  • Hydrocephalus / surgery
  • Hydrocephalus, Normal Pressure / physiopathology*
  • Hydrocephalus, Normal Pressure / surgery
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Pitch Perception / physiology*
  • Reaction Time / physiology
  • Reference Values
  • Syndrome