Moebius syndrome associated with pituitary dwarfism and hypoplastic optic disc

Acta Paediatr Jpn. 1993 Apr;35(2):144-7. doi: 10.1111/j.1442-200x.1993.tb03026.x.

Abstract

A 17 year old male patient with Moebius syndrome with pituitary dwarfism and unilateral hypoplastic optic disc is presented. Although there have been several reports of an association of Moebius syndrome and pituitary dysfunction, growth hormone deficiency has not been reported previously. These associations may give some insight into the pathogenesis of Moebius syndrome.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Dwarfism, Pituitary / congenital*
  • Dwarfism, Pituitary / diagnosis
  • Dwarfism, Pituitary / drug therapy
  • Facial Paralysis / congenital*
  • Facial Paralysis / diagnosis
  • Growth Hormone / therapeutic use
  • Humans
  • Male
  • Ophthalmoplegia / congenital*
  • Ophthalmoplegia / diagnosis
  • Syndrome

Substances

  • Growth Hormone