Trisomy 11 with loss of the Y chromosome and trisomy 13 in a case of de novo acute myeloid leukemia

J Meletis; M Samarkos; D Abazis; E Michali; S Vavourakis; E Plata; J Rombos; K Konstantopoulos; K Pangalos; X Yataganas; D Loukopoulos

doi:10.1016/0165-4608(95)00161-1

Trisomy 11 with loss of the Y chromosome and trisomy 13 in a case of de novo acute myeloid leukemia

Cancer Genet Cytogenet. 1996 Jan;86(1):65-8. doi: 10.1016/0165-4608(95)00161-1.

Authors

J Meletis¹, M Samarkos, D Abazis, E Michali, S Vavourakis, E Plata, J Rombos, K Konstantopoulos, K Pangalos, X Yataganas, D Loukopoulos

Affiliation

¹ First Department of Internal Medicine, University of Athens School of Medicine, Greece.

PMID: 8616790
DOI: 10.1016/0165-4608(95)00161-1

Abstract

We report a man with de novo acute myeloid leukemia (M4 of the FAB classification) bearing two abnormal clones in the bone marrow cells. The clones showed trisomy 11 with loss of the Y chromosome and trisomy 13, respectively.

Publication types

Case Reports

MeSH terms

Adult
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Bone Marrow / diagnostic imaging
Chromosomes, Human, Pair 11*
Chromosomes, Human, Pair 13*
Gene Deletion*
Humans
Karyotyping
Leukemia, Myeloid, Acute / diagnosis
Leukemia, Myeloid, Acute / drug therapy
Leukemia, Myeloid, Acute / genetics*
Male
Remission Induction
Trisomy*
Ultrasonography
Y Chromosome*