FTY720, a novel immunosuppressant possessing unique mechanisms. I. Prolongation of skin allograft survival and synergistic effect in combination with cyclosporine in rats

Transplant Proc. 1996 Apr;28(2):1056-9.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Cyclosporine / therapeutic use*
  • Drug Synergism
  • Drug Therapy, Combination
  • Fingolimod Hydrochloride
  • Graft Survival / drug effects*
  • Immunosuppressive Agents / therapeutic use*
  • Interleukin-2 / biosynthesis
  • Major Histocompatibility Complex
  • Male
  • Propylene Glycols / therapeutic use*
  • Rats
  • Rats, Inbred F344
  • Rats, Inbred Lew
  • Rats, Inbred Strains
  • Skin Transplantation / immunology*
  • Sphingosine / analogs & derivatives
  • Spleen
  • T-Lymphocytes / drug effects
  • T-Lymphocytes / immunology
  • Transplantation, Homologous

Substances

  • Immunosuppressive Agents
  • Interleukin-2
  • Propylene Glycols
  • Cyclosporine
  • Fingolimod Hydrochloride
  • Sphingosine