[Drug induced fatal anaphylactic shock in Denmark 1968-1990]

Ugeskr Laeger. 1996 Jun 3;158(23):3316-8.
[Article in Danish]

Abstract

Based on notifications to the Danish Committee on Adverse Drug Reactions and to the Central Death Register, 30 cases of fatal drug-induced anaphylactic shock were identified during the period 1968-1990. The most frequent causes were contrast media for X-ray examinations, antibiotics, and extracts of allergens. Nine cases occurred outside hospital; they were mainly caused by the use of allergen extracts of moulds for desensitization in general practice. Fatal drug-induced anaphylactic shock is rare, estimated in the present study at 0.3 cases per million inhabitants per year.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Adverse Drug Reaction Reporting Systems*
  • Aged
  • Allergens / adverse effects
  • Anaphylaxis / chemically induced*
  • Anaphylaxis / mortality
  • Anesthetics / adverse effects
  • Anti-Bacterial Agents / adverse effects
  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects
  • Contrast Media / adverse effects
  • Denmark / epidemiology
  • Female
  • Humans
  • Male
  • Middle Aged

Substances

  • Allergens
  • Anesthetics
  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Contrast Media